COMPLEX FORMATION BETWEEN SYNTHETIC DETERGENTS AND PROTEINS
نویسندگان
چکیده
منابع مشابه
Interaction between Proteins and Synthetic Detergents
Attempts have been made to explain the action of certain proteindenaturing agents, such as organic solvents, urea, guanidine halides, and salicylates, in terms of (a) physical solvent effects (cf. (4)) or (b) unspecified intermediary combination between denaturant and protein (cf. (5)). Recent work has shown that the denaturing effect of guanidine hydrochloride, one of the most powerful denatur...
متن کاملThe Denaturation of Proteins by Synthetic Detergents and Bile Salts
All the synthetic detergents and bile salts I have tried denature proteins such as hemoglobin and egg albumin at the isoelectric point 1 and keep the denatured isoelectric protein in solution. Some detergents in sufficiently high concentration can prevent the precipitation of denatured protein by trichloracetic acid, tungstic acid, and acid ferric sulfate. In fact, the origin of the present inv...
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The bactericidal and bacteriostatic actions of soaps have been recognized for many years. Detailed studies by Eggerth (1) on the germicidal action of soaps have shown the importance of such factors as length of hydrocarbon chain, chemical configuration, effect of hydrogen ion concentration, effect of serum, etc. Avery (2) demonstrated the selective germicidal action of soap on microorganisms, a...
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Interactions between membrane proteins and detergents are important in biophysical and structural studies and are also biologically relevant in the context of folding and transport. Despite a paucity of high-resolution data on protein-detergent interactions, novel methods and increased computational power enable simulations to provide a means of understanding such interactions in detail. Simula...
متن کاملSynthetic detergents in bile-salt-deficient steatorrhoea.
1. Fat malabsorption caused by bile-salt deficiency is not easily corrected by standard therapy. It has been shown in rats with bile-salt deficiency that non-ionic detergents can replace bile salts and improve fat absorption. A careful assessment of the place of synthetic detergents such as Tween in human therapy has not been reported. 2. The effects of Tween were studied in 13 patients with bi...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1943
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)51272-2